陳 玫潔
專任老師
姓名 陳 玫潔
電子郵件 mcchen@tmu.edu.tw
聯絡電話 02-27361661#3910
研究專長 Immunology Inflammation Signal Transduction

Research Description
1. Molecular and cellular analyses of the roles of lymphotoxin beta receptors in acquired immunity and inflammation.
開課
For undergraduate students
Microbiology and Immunology- course A (for medical and dental students)

1.Introduction to the immune system

2.T cell receptors and major histocompatibility complex molecules

3.Antigen processing and presentation

4.Cell cooperation in the antibody response

5.Cytokines and cytokine receptors

6.Immune responses to infectious agents

Microbiology and Immunology- course B, C, D (for other students)

1.Nonspecific defenses of the host

2.Specific defenses of the host

3.Disorders associated with the immune system

4.Practical application of immunology

Introduction to Molecular Biology

1.DNA and RNA structure

2.Gene transcription

3.RNA processing

4.Translation

5.Cell mitosis and meiosis

6.Cell cycle and regulation

7.The application in molecular biology

Introduction to Immunology

1.Introduction to the immune system

2.Lymphoid organs and immune cells

3.T cell receptors and major histocompatibility complex

4.Cellular immunity

5.Immunoregulation

6.The application of immunology

For graduate students

Discussion in immunology

Tumor Necrosis Factor and Tumor Necrosis Factor Receptor Superfamilies

Individual studies in medical research (I)

Strategy for Molecular Biology Research: Transcriptional regulation study

Individual studies in medical research (II)

Experimental Design for Inflammation Research

Vaccine

1.The role of CpG motifs in Immunostimulation

2.Dendritic Cell-Based Immunotherapy for Cancer

Cancer epidemiology

Immune system and cancer　

Molecular epidemiology

1.The study of cell cycle control in cancer epidemiology

2.Immunological assessments of molecular epidemiology: the application of flow cytometry
職稱 副教授
任別 專任
學歷 國立陽明大學 微生物免疫學 博士 1993 至1998
服務機關名稱 單位 職務
台北醫學大學 醫學系微生物免疫學科 助理教授
國立陽明大學 微生物免疫學 中心 博士後研究
年度 論文名稱
2011 1. Chien, Pei-Ju, Yeh, Jiann-Horng, Chiu, Hou-Chang, Hsueh, Yu-Mei, Chen, Chien-Tsu, Chen, Mei-Chieh; Shih, Chwen-Ming(2011).Inhibition of Peripheral Blood Natural Killer Cell Cytotoxicity in Myasthenia Gravis Patients Treated with Plasmapheresis. European Journal of Neurology.(accep):-.
2010 2. Hsu MJ, Chang CK, Chen MC, Chen BC, Ma HP, Hong CY, Lin CH(2010).Apoptosis signal-regulating kinase 1 in peptidoglycan-induced COX-2 expression in macrophages. J Leukoc Biol.(87):1069-1082.
2009 3. Yu CC, Hsu MJ, Kuo ML, Chen RF, Chen MC, Bai KJ, Yu MC, Chen BC, Lin CH(2009).Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway. The Journal of Immunology.(182):7916-7927.
2009 4. Kuo CT, Chen BC, Yu CC, Weng CM, Hsu MJ, Chen CC, Chen MC, Teng CM, Pan SL, Bien MY, Shih CH, Lin CH(2009).Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells. J Biomed Sci.(16):43-.
2008 5. Kuo CT, Chen BC, Hsu MJ, Chen CC, Chen MC, Teng CM, Pan SL, Bien MY, Shih SH, Lin CH(2008).Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells. Journal of Biomedical Science.(submit):-.
2007 6. Hsu MJ, Hsu CY, Chen BC, Chen MC, Ou George, Lin CH(2007).ASK1 in Amyloid ß Peptide-Induced Cerebral Endothelial Cell Apoptosis. The Journal of Neuroscience.(27):5719-5729.
2006 7. You RI, Chen MC, Wang HW, Chou YC, Hsieh SL(2006).Inhibition of Lymphotoxin-beta Receptor (LTbR)-mediated Cell Death by Survivin-deltaEx3. Cancer Research.(66):3051-3061.
2006 8. Lin CH, Cheng HW, Hsu MJ, Chen MC, Lin CC, Chen BC(2006).c-Src Mediates Thrombin-Induced NF-{kappa}B Activation and IL-8/CXCL8 Expression in Lung Epithelial Cells. The Journal of Immunology.(177):3427-3438.
2004 9. Chen BC, Yu CC, Lei HC, Chang MS, Hsu MJ, Huang CL, Chen MC, Sheu JR, Chen TF, Chen TL, Inou(2004).Bradykinin B2 receptor mediates NF-kappaB activation and cyclooxygenase-2 expression via the Ras/Raf-1/ERK pathway in human airway epithelial cells. The Journal of Immunology.(173):5219-5228.
2003 10. Chen MC, Hwang MJ, Chou YC, Chen WH, Cheng G, Nakano H, Luh TY, Mai SC, and Hsieh SL(2003).The Role of Apoptosis Signal-regulating Kinase 1 in Lymphotoxin-beta Receptor-mediated Cell Death. The Journal of Biological Chemistry.(278):16073-16081.
年度 論文名稱
2019 2. Chen MC(2009).NF-kappaB and AP-1 regulate RANTES expression induced by lymphotoxin beta receptor activation. The FEBS journal.(276):-.
2010 1. Chen MC, Chen YW, Lin YC, Wu MP(2010).Selective roles of MAPKs in regulating the post-transcriptional stability of IL-8 mRNA by CCN2. 11664 - FASEB SRC: Post-transcriptional Control of Gene Expression: Mechanisms of mRNA Decay.():-.
2008 3. Chen MC, Liao SP, Chou MC(2008).THE POTENTIAL ROLES OF OXIDIZED LOW-DENSITY LIPOPROTEIN IN REGULATION OF DENDRITIC CELL ADHESION. the FEBS journal.(275):257-.
2006 4. You RI, Chen MC, Wang HW, Chou YC, Lin CH, Hsieh SL(2006).Inhibition of Lymphotoxin-beta Receptor (LTbR)-mediated Cell Death by Survivin-DEx3. The Journal of Immunology (AAI Abstract Number: 541).():-.